糖基化肽类药物的研究进展 - 香港千禾出版集团有限公司

摘要：肽药是一种由氨基酸残基有序连接而成的独特药物形式，因其高亲和力、高特异性、低免疫原性和经济的生产成本而备受重视。但是肽药的临床应用往往受到稳定性差、半衰期短等因素的限制，而糖基化修饰在改善多肽理化性质和生物活性方面具有显著优势。本综述聚焦于多肽的糖基化修饰类型及糖肽药物在降糖、抗菌、抗病毒方面的应用，旨在为治疗性肽的设计和优化提供指导，并深入挖掘糖肽类药物在疾病治疗中的潜力。

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